Pycnogenol and PMS


The subjects were 116 women aged 18-48 years. The first 2 menstrual cycles served as a control period; during the subsequent 2 menstrual cycles women received either a Pycnogenol® (PYC) supplement (60 mg/day) or a placebo in identical capsule form. One further cycle was monitored after cessation of capsule administration.


Women were assigned to either a group with low menstrual pain or a group with dysmenorrhea. In women with low menstrual pain, no significant difference for lowering of pain scores was found. In contrast, women with dysmenorrhea had a significantly lower pain score and required statistically significantly less analgesic medication during supplementation with PYC.


The number of days women required analgesic medication was found to be statistically significantly lowered in the PYC group. Even after discontinuation of PYC supplementation, the required analgesic medication remained significantly decreased.


We conclude from this study that the analgesic-sparing effect of Pycnogenol increases with duration of supplementation and benefits persist even after discontinuation.


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